Iimpawu ze-pharmacological and toxicological properties ze-furazolidone ziye zahlaziywa ngokufutshane. Phakathi kwezenzo ezibaluleke kakhulu ze-pharmacological ze-furazolidone kukuvinjelwa kwe-mono- kunye ne-diamine oxidase imisebenzi, ebonakala ixhomekeke, ubuncinane kwezinye iintlobo, kubukho be-flora yamathumbu. Ichiza likwabonakala liphazamisana nokusetyenziswa kwe-thiamin, ekusenokwenzeka ukuba iluncedo ekuvelisweni kwe-anorexia kunye nokuncipha kobunzima bomzimba wezilwanyana ezinyangwayo. I-Furazolidone yaziwa ngokubangela imeko ye-cardiomyopathy kwi-turkeys, enokusetyenziswa njengomzekelo wokufunda ukusilela kwe-alpha 1-antitrypsin kumntu. Iyeza lelona liyityhefu kwizinto ezetyisayo. Iimpawu eziyityhefu ezabonwayo yayizezendalo yovalo. Iimvavanyo ziyaqhubeka kule labhoratri ukuzama ukucacisa indlela(ii)ndlela eziziswa ngayo le tyhefu. Akuqinisekanga ukuba ukusetyenziswa kwe-furazolidone kwi-dose yonyango ecetyiswayo kuya kubangela iintsalela zeziyobisi kwiithishu zezilwanyana eziphathwayo. Lo ngumba obalulekileyo kwimpilo yoluntu njengoko ichiza libonisiwe ukuba linomsebenzi we-carcinogenic. Kubalulekile ukuba indlela elula kwaye enokwethenjelwa yokuchonga kunye noqikelelo lweentsalela ze-furazolidone zenziwe. Umsebenzi omninzi uyafuneka ukucacisa indlela yokusebenza kunye neziphumo ze-biochemical ezibangelwa lichiza kuzo zombini i-host kunye ne-infective organisms.
Ixesha lokuposa: Oct-08-2021