Izakhiwo ze-pharmacological kanye ne-toxicological ze-furazolidone zibuyekezwe kafushane.Phakathi kwezenzo ezibaluleke kakhulu ze-pharmacological ze-furazolidone ukuvimbela imisebenzi ye-mono- ne-diamine oxidase, okubonakala sengathi incike, okungenani kwezinye izinhlobo, ebukhoneni bezitshalo zamathumbu.Umuthi futhi ubonakala uphazamisa ukusetshenziswa kwe-thiamin, okungenzeka ukuthi iwusizo ekukhiqizeni i-anorexia kanye nokuncipha kwesisindo somzimba wezilwane ezilashwayo.I-Furazolidone yaziwa ngokudala isimo se-cardiomyopathy kuma-turkeys, engasetshenziswa njengemodeli ukutadisha ukuntula kwe-alpha 1-antitrypsin kumuntu.Umuthi unobuthi kakhulu ezilwaneni ezelusayo.Izimpawu ezinobuthi ezabonwa kwakungezokwethuka.Ukuhlolwa kuyaqhubeka kule labhorethri ukuzama ukuchaza indlela(izi)ndlela okwenziwa ngazo lobu buthi.Akuqinisekwa ukuthi ukusetshenziswa kwe-furazolidone ngethamo elinconyiwe lokwelapha kungaholela ezinsalela zezidakamizwa ezicutshini zezilwane ezilashwayo.Lolu wudaba olubalulekile empilweni yomphakathi njengoba umuthi ukhonjiswe ukuthi unomsebenzi we-carcinogenic.Kubalulekile ukuthi kuqanjwe indlela elula nethembekile yokuhlonza nokulinganisa izinsalela ze-furazolidone.Kudingeka umsebenzi owengeziwe ukuze kucaciswe indlela yokwenza kanye nemiphumela ye-biochemical ebangelwa umuthi kukho kokubili umsingathi kanye nezinto ezithathelwanayo.
Isikhathi sokuthumela: Oct-08-2021